Clinic protocol. Clinic-protocol / off-label extrapolation — not an FDA-approved regimen.
Typical — reference only
Intranasal ~300-450 mcg/day (Russian label); SubQ is community-only
Worked reconstitution example
SubQ (community): 5 mg vial + 2 mL BAC = 2.5 mg/mL; 250 mcg = 10 U on U-100. Intranasal is the trial route - dose by mcg/spray.
Titration
Cycles ~14 days then washout
Units are not milligrams. mg-vs-mcg confusion drives documented 5–1000× overdoses — always recompute for your own vial (use the calculator →).
Removal from Category 2 ≠ legal to compound ≠ FDA-approved. No active US compounding pathway; treat as gray-market RUO. Verify against FDA docket.
StatusCategory 2 — restricted
503A bulksNot on the bulks list
Category 2 (2026)Removed earlier (Sept 2024 referral) but NOT in the Apr 2026 wave or Jul 2026 PCAC; vendor 'returned to Category 1' claims are FALSE
PCAC reviewnone scheduled
WADANot listed
03Evidence — the honest read
Bhuman trials
Small Russian human data (Medvedev 2008, n=62: anxiolytic comparable to benzodiazepine); unreplicated in the West. Russia-approved nasal drops since 2009.
Contraindications
- Pregnancy/breastfeedinghard stop
- Children
- Hypersensitivity
Key interactions
- Serotonergic agents (SSRI/SNRI/MAOI) - theoretical serotonin-syndrome additive risk (caution, low confidence)
- Benzodiazepines (animal-derived synergy claim - extrapolation)
Serious signals
- Long-term safety unknown (longest trials ~30 days)
- Gray-market integrity/immunogenicity
Monitoring
None validated.
01Medvedev 2008
+PepTrack research dossier — iterations 1–4, 584 de-duplicated sources, adversarially verified.
Not medical or legal advice. Educational / harm-reduction reference. Regulatory and dosing claims in this field move monthly — re-verify against primary sources (FDA docket FDA-2025-N-6895, DailyMed, ClinicalTrials.gov) before acting.
Last reviewed — 2026-06-13 · confidence: medium